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6-(Difluoromethyl)Indole
CAS: 127956-27-8
Ref. 3D-FD77842
50mg | To inquire | ||
100mg | To inquire | ||
250mg | To inquire |
Product Information
- 6-(difluoromethyl)-1H-indole
6-(Difluoromethyl)Indole is a synthetic molecule that functions as a pyrrole. 6-(Difluoromethyl)Indole is an analogue of the natural substrate tryptophan and can be used to study the mechanism of enzyme-catalyzed reactions. It reacts with the enzyme indoleamine 2,3-dioxygenase (IDO), which is involved in the metabolism of tryptophan, and forms a covalent bond with cysteine residues on IDO's active site. This binding stabilizes the enzyme and prevents it from degrading tryptophan, which leads to an increase in tryptophan levels in the body. The formation of this compound can also be tracked by chromatography, making it useful for studying mechanisms of enzymatic regulation.
Chemical properties
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