(2,4-Difluoro-3-formylphenyl)boronic acid
CAS: 870718-06-2
Ref. 3D-FD86661
1g | Discontinued | ||
5g | Discontinued | ||
10g | Discontinued |
Product Information
- Boronic acid, (2,4-difluoro-3-formylphenyl)-
- 2,4-Difluoro-3-formylbenzeneboronic acid
- Boronic acid, B-(2,4-difluoro-3-formylphenyl)-
- B-(2,4-Difluoro-3-formylphenyl)boronic acid
The compound 2,4-difluoro-3-formylphenyl)boronic acid is an imprinting agent that has been shown to bind with human serum albumin. The binding is characterized by a red shift in the absorption spectrum and the formation of a cavity at the boron atom. This cavity can be used for the detection of ligands with a macrocyclic structure, such as isophthalaldehyde. The affinity of this ligand for 2,4-difluoro-3-formylphenyl)boronic acid was determined using competitive inhibition studies. It was found that the binding constant (Ki) for isophthalaldehyde was 4.0 x 10 M and that it had an affinity of 3.1 x 10 M for boronic acids in general.