5-Ethyl-3-[[2-Fluoro-4-[2-(3-Methylbutoxycarbonylsulfamoyl)Phenyl]Phenyl]Methyl]-2-Propylimidazole-4-Carboxylic Acid

CAS: 157566-60-4

Ref. 3D-FE103231

Product Information

• Name: 5-Ethyl-3-[[2-Fluoro-4-[2-(3-Methylbutoxycarbonylsulfamoyl)Phenyl]Phenyl]Methyl]-2-Propylimidazole-4-Carboxylic Acid
• Synonyms: 4-((5-(2-Benozyl)benzyloxycarbonyl-4-ethyl-2-n-propylimidazole-1-yl)methyl)-3-fluoro-2'- isoamyloxycarbonylaminosulfonyl-1,1'-biphenyl, 4-ethyl-1-[(3-fluoro-2'-{[(3-methylbutoxy)carbonyl]sulfamoyl}biphenyl-4-yl)methyl]-2-propyl-1H-imidazole-5-carboxylic acid

Description

5-Ethyl-3-[[2-Fluoro-4-[2-(3-Methylbutoxycarbonylsulfamoyl)Phenyl]Phenyl]Methyl]-2-Propylimidazole-4-Carboxylic Acid is a drug that inhibits the angiotensin II receptor by binding to it. It has been shown to lower blood pressure in hypertensive rats, and has been found to have affinity for the AT1 receptor. 5Et4ICCA blocks angiotensin II receptors and prevents activation of these receptors. The drug has shown efficacy in vivo against angiotensin II induced hypertension in rats by inhibiting angiotensin binding sites.

• Brand: Biosynth

Chemical properties

• Molecular weight: 559.65 g/mol
• Formula: C₂₈H₃₄FN₃O₆S
• Purity: Min. 95%
• InChI: InChI=1S/C28H34FN3O6S/c1-5-9-25-30-23(6-2)26(27(33)34)32(25)17-20-13-12-19(16-22(20)29)21-10-7-8-11-24(21)39(36,37)31-28(35)38-15-14-18(3)4/h7-8,10-13,16,18H,5-6,9,14-15,17H2,1-4H3,(H,31,35)(H,33,34)
• InChI key: InChIKey=GYEABWYHBNPBGW-UHFFFAOYSA-N
• SMILES: CCCc1nc(CC)c(C(=O)O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCCC(C)C)cc1F