(4E)-4-(Ethoxymethylene)-2-phenyl-1,3-oxazol-5(4H)-one

CAS: 15646-46-5

Ref. 3D-FE123928

Product Information

• Name: (4E)-4-(Ethoxymethylene)-2-phenyl-1,3-oxazol-5(4H)-one
• Synonyms: 5(4H)-oxazolone, 4-(ethoxymethylene)-2-phenyl-, (4E)-, (4E)-4-(ethoxymethylidene)-2-phenyl-1,3-oxazol-5(4H)-one, (4Z)-4-(ethoxymethylidene)-2-phenyl-1,3-oxazol-5(4H)-one, 2-Oxazolin-5-one, 4-ethoxymethylene-2-phenyl-, 2-Phenyl-1-4-heteromethylene-5-oxazolone, 2-Phenyl-4-(ethoxymethylene)-2-oxazolinone, 2-Phenyl-4-(ethoxymethylene)oxazolone, 2-Phenyl-4-ethoxymethylene-5-oxazolone, 4-(Ethoxymethylene)-2-phenyl-5(4H)-oxazolone, 4-(ethoxymethylidene)-2-phenyl-1,3-oxazol-5(4H)-one, 4-Ethoxymethylene-2-phenyl oxazolone, 4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one, 4-Ethoxymethylene-2-phenyl-5-oxazolone, 5(4H)-Oxazolone, 4-(ethoxymethylene)-2-phenyl-, 5(4H)-Oxazolone, 4-(ethoxymethylene)-2-phenyl- (9CI), Oxazolone, Oxazolone (allergen), Oxazolone (sensitizing agent)

Description

4E-4-(Ethoxymethylene)-2-phenyl-1,3-oxazol-5(4H)-one is an antiinflammatory agent that inhibits the transfer of kinetic energy from one molecule to another in a chemical reaction. 4E-4-(Ethoxymethylene)-2-phenyl-1,3-oxazol-5(4H)-one has shown inhibitory properties against cyclic peptides and dextran sulfate. This compound also has antiinflammatory activity, inhibiting proinflammatory cytokines such as TNFα and IL-6. 4E-4-(Ethoxymethylene)-2-phenyl-1,3-oxazol-5(4H)-one is being studied as a possible treatment for inflammatory bowel disease. It binds to toll like receptor 2 (TLR2) and blocks NFκB activation through transcription polymerase chain reactions (PCRs). The drug also has antidiabetic

• Brand: Biosynth

Chemical properties

• Molecular weight: 217.22 g/mol
• Formula: C₁₂H₁₁NO₃
• Purity: Min. 95%
• InChI: InChI=1S/C12H11NO3/c1-2-15-8-10-12(14)16-11(13-10)9-6-4-3-5-7-9/h3-8H,2H2,1H3/b10-8+
• InChI key: InChIKey=SJHPCNCNNSSLPL-CSKARUKUSA-N
• SMILES: CCO/C=C1/N=C(c2ccccc2)OC1=O