[4-(4-Ethylpiperazin-1-yl)phenyl]amine
CAS: 115619-01-7
Ref. 3D-FE125043
2g | Discontinued | ||
5g | Discontinued | ||
10g | Discontinued | ||
25g | Discontinued | ||
50g | Discontinued |
Product Information
- 4-(4-ethylpiperazin-1-yl)anilinebenzenamine
- 4-(4-ethyl-1-piperazinyl)-
- 4-(4-Ethyl-1-piperazinyl)benzenamine
- 4-(4-Ethyl-Piperazin-1-Yl)-Phenylamine
- 4-(4-Ethylpiperazin-1-yl)benzenamine
- 4-(4-Ethylpiperazine-1-yl)aniline
- 4-(4-Ethylpiperazino)Aniline
- 4-(4-ethylpiperazin-1-YL)aniline
- 4-(4-ethylpiperazin-1-YL)phenylamine
- Akos B021943
- See more synonyms
- Akos Bb-8659
- Art-Chem-Bb B021943
- Benzenamine, 4-(4-ethyl-1-piperazinyl)-
- Timtec-Bb Sbb007132
4-(4-Ethylpiperazin-1-yl)phenyl]amine (NVP-AEW541) is a novel investigational drug with potent antitumor activity. It has shown to inhibit the growth of bladder cancer cells in vitro. Mechanistically, NVP-AEW541 induces autophagy and cell death in bladder cancer cells. The drug has been tested for its efficacy in a xenograft model of bladder cancer and an orthotopic mouse model of bladder cancer. In these models, NVP-AEW541 showed potent antitumor activity, including complete tumor regression, reduced tumor weight and volume, decreased proliferation index, and increased apoptosis index.