Ethyl 2-(ethoxymethylene)-3-oxobutanoate

CAS: 3788-94-1

Ref. 3D-FE140261

Product Information

• Name: Ethyl 2-(ethoxymethylene)-3-oxobutanoate
• Synonyms: 2-(Ethoxymethylene)-3-oxo-butanoic acid ethyl ester, 2-(Ethoxymethylene)acetoacetic acid ethyl ester, 2-Acetyl-3-ethoxyacrylic acid ethyl ester, 2-Ethoxymethylene-3-oxobutanoic acid ethyl ester, 2-[1-Ethoxymethylidene]-3-oxo-butyric acid ethyl ester, Acetoacetic acid, 2-(ethoxymethylene)-, ethyl ester, Butanoic acid, 2-(ethoxymethylene)-3-oxo-, ethyl ester, Ethyl (ethoxymethylene)acetoacetate, Ethyl 2-(Ethoxymethylidene)-3-Oxobutanoate, Ethyl 2-(ethoxymethylene)-3-oxobutyrate, Ethyl 2-acetyl-3-ethoxyacrylate, Ethyl 2-ethoxymethylene-3-oxobutanoate, Ethyl 2-ethoxymethylidene-acetoacetate, NSC 32775, ethyl (2E)-2-(ethoxymethylidene)-3-oxobutanoate, ethyl (2Z)-2-(ethoxymethylidene)-3-oxobutanoate

Description

Ethyl 2-(ethoxymethylene)-3-oxobutanoate is an industrial chemical that is used as a precursor to acetoacetate. It is produced by the condensation of formaldehyde and ethyl acetoacetate, which yields two molecules of ethyl 2-(ethoxymethylene)-3-oxobutanoate. This reaction can be performed in three steps, with the first step involving the addition of formaldehyde and hydrazine to acetoacetate. The second step involves heating the reaction mixture until it boils, followed by cooling and filtering. The third step requires refluxing for six hours before distilling off the liquid. Ethyl 2-(ethoxymethylene)-3-oxobutanoate can also be synthesized from orthoformic acid and ethyl acetoacetate in an experiment that produces 1 mole of product for every mole of starting material.

• Brand: Biosynth

Chemical properties

• Molecular weight: 186.21 g/mol
• Formula: C₉H₁₄O₄
• Purity: Min. 95%
• InChI: InChI=1S/C9H14O4/c1-4-12-6-8(7(3)10)9(11)13-5-2/h6H,4-5H2,1-3H3/b8-6-
• InChI key: InChIKey=FNASCUBBFNCFQO-VURMDHGXSA-N
• SMILES: CCO/C=C(/C(C)=O)C(=O)OCC