Ethyl4-amino-2-hydroxypyrimidine-5-carboxylate

CAS: 20187-46-6

Ref. 3D-FE147838

Product Information

• Name: Ethyl4-amino-2-hydroxypyrimidine-5-carboxylate
• Synonyms: 4-Amino-2-oxo-1,2-dihydro-pyrimidine-5-carboxylic acid ethyl ester, 5-Pyrimidinecarboxylic Acid, 4-Amino-2-Hydroxy-, Ethyl Ester, 5-Pyrimidinecarboxylic acid, 6-amino-1,2-dihydro-2-oxo-, ethyl ester, 6-Amino-2-oxo-1,2-dihydro-pyrimidine-5-carboxylic acid ethyl ester, Ethyl 6-amino-2-oxo-1,2-dihydropyrimidine-5-carboxylate, Ethyl4-Amino-2-hydroxy-5-pyrimidinecarboxylate

Description

Ethyl 4-amino-2-hydroxypyrimidine-5-carboxylate (EAHPC) is an enzyme hydrolysis product that is metabolically converted to ethyl pyrimidine carboxylate (EPC). EAHPC is a germ cell mutagen and may be a carcinogen. It has been shown to cause chromosome damage in spermatocytes and the subsequent production of germ cells with chromosomal aberrations. EAHPC has low activity as a mutagen, but it can have a maximal effect on the induction of mutations. The mechanism by which EAHPC causes these effects is not well understood.

• Brand: Biosynth

Chemical properties

• Molecular weight: 183.16 g/mol
• Formula: C₇H₉N₃O₃
• Purity: Min. 95%
• InChI: InChI=1S/C7H9N3O3/c1-2-13-6(11)4-3-9-7(12)10-5(4)8/h3H,2H2,1H3,(H3,8,9,10,12)
• InChI key: InChIKey=GGHDCMZITFQXRE-UHFFFAOYSA-N
• SMILES: CCOC(=O)c1cnc(=O)[nH]c1N