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5-(N-Ethyl-N-isopropyl) amiloride
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5-(N-Ethyl-N-isopropyl) amiloride

CAS: 1154-25-2

Ref. 3D-FE16546

1mg
138.00 €
2mg
194.00 €
5mg
310.00 €
10mg
436.00 €
25mg
582.00 €
Estimated delivery in United States, on Tuesday 18 Feb 2025

Product Information

Name:
5-(N-Ethyl-N-isopropyl) amiloride
Synonyms:
  • 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide
  • 2-Pyrazinecarboxamide, 3-amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-
  • 3-amino-6-chloro-N-(diaminomethylidene)-5-[ethyl(propan-2-yl)amino]pyrazine-2-carboxamide
  • Ethylisopropylamiloride
  • L 593754
  • Mh 12-43
  • Pyrazinecarboxamide, 3-amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-
  • Pyrazinecarboxamide, N-amidino-3-amino-6-chloro-5-(ethylisopropylamino)-
  • 5-(N-Ethyl-N-Isopropyl) Amiloride
  • 5-(N-Ethyl-N-isopropyl)amiloride
  • See more synonyms
Description:

5-(N-Ethyl-N-isopropyl) amiloride is a cyclase inhibitor that has been shown to have anti-cancer effects in solid tumours. It blocks the production of cAMP and therefore inhibits the activation of protein kinase A, which leads to neuronal death. The drug also shows potent activity against tumours that express growth factor β1 (GFβ1). In addition, 5-(N-Ethyl-N-isopropyl) amiloride has been shown to inhibit the proliferation of HL60 cells by blocking both DNA synthesis and RNA synthesis. This inhibition is caused by an increase in proton release and polymerase chain reaction (PCR) amplification of DNA.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
299.76 g/mol
Formula:
C11H18ClN7O
Purity:
Min. 95%
Color/Form:
Powder
InChI:
InChI=1S/C11H18ClN7O/c1-4-19(5(2)3)9-7(12)16-6(8(13)17-9)10(20)18-11(14)15/h5H,4H2,1-3H3,(H2,13,17)(H4,14,15,18,20)
InChI key:
InChIKey=QDERNBXNXJCIQK-UHFFFAOYSA-N
SMILES:
CCN(c1nc(N)c(C(=O)N=C(N)N)nc1Cl)C(C)C
MDL:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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