cis-Entacapone
CAS: 145195-63-7
Ref. 3D-FE22677
1mg | Discontinued | ||
2mg | Discontinued | ||
5mg | Discontinued | ||
10mg | Discontinued | ||
25mg | Discontinued |
Product Information
- (2Z)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide(Z)-Entacapone
- (2Z)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide
- (Z)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide
- (Z)-Entacapone
- 2-Propenamide, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-, (2Z)-
- 2-Propenamide, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-, (Z)-
cis-Entacapone is a drug that is used to treat Parkinson's disease. It is a prodrug of entacapone, which is an inhibitor of catechol-O-methyltransferase (COMT), an enzyme that breaks down catecholamines such as dopamine and norepinephrine. cis-Entacapone has been shown to be effective in the treatment of Parkinson's disease when combined with levodopa, carbidopa, or benserazide. In addition, this drug has low bioavailability and poor solubility in acidic ph.