4-Epianhydrotetracycline hydrochloride hydrate

CAS: 4465-65-0, 7518-17-4

Ref. 3D-FE22716

Product Information

• Name: 4-Epianhydrotetracycline hydrochloride hydrate
• Synonyms: (4R,4aS,12aS)-4-(Dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide hydr ochloride
• Brand: Biosynth
• Description: 4-Epianhydrotetracycline hydrochloride hydrate is a chemical compound that inhibits the activation of protein kinase C (PKC) and blocks the apoptosis pathway. It has been shown to induce apoptosis in prostate cancer cells and also inhibits the proliferation of human microvessel endothelial cells. 4-Epianhydrotetracycline hydrochloride hydrate is stable in both human serum and wastewater, which makes it an ideal drug for treating many types of cancers. It is also used in pharmaceutical drugs as a cytochalasin, which are used to treat angina pectoris by reducing oxygen uptake by erythrocytes, thereby inhibiting oxidative phosphorylation. 4-Epianhydrotetracycline hydrochloride hydrate prevents mitochondrial cytochrome c release, thus blocking the apoptotic pathway in cells. This chemical compound may act as a regulatory molecule that affects energy metabolism and epidermal growth factor (EGF)

Chemical properties

• Molecular weight: 462.88 g/mol
• Formula: C₂₂H₂₃ClN₂O₇
• Purity: Min. 95%