Ethacrynic acid L-cysteine adduct
CAS: 51246-37-8
Ref. 3D-FE22849
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Product Information
- S-[2-[4-(Carboxymethoxy)-2,3-dichlorobenzoyl]butyl]-L-cysteine
- cysteine-ethacrynic acidCysteine-ethacrynic acid adductEthacrynic acid-cysteine complex
Ethacrynic acid L-cysteine adduct (EAC) is a non-competitive inhibitor of phosphatases. It is a β-unsaturated ketone that has been shown to inhibit the phosphatase activity of pepsin and other enzymes. EAC binds to glutathione, forming an inactive covalent bond. The glutathione conjugate is inactivated by incubation with aminopyrine and pepsin, which degrades the glutathione moiety. This leads to the formation of a phosphatase inhibitor that is catalytic and competitive in nature. EAC can be used as a reagent for cell culture media or tissue sections, where it inhibits the activity of phosphatases that might interfere with certain enzymatic reactions.
Chemical properties
Technical inquiry about: 3D-FE22849 Ethacrynic acid L-cysteine adduct
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