Ethyl cyanoethylphenylacetate

CAS: 718-71-8

Ref. 3D-FE23041

Product Information

• Name: Ethyl cyanoethylphenylacetate
• Synonyms: 2-Cyano-2-phenyl-butyric acid ethyl estera-Cyano-a-ethyl-benzeneacetic acid ethyl esterNSC 6912, (R,S)-2-Cyano-2-Phenyl-Butyric Acid Ethyl Ester, (R,S)-Ethylphenylcyano-aceticacidethylester, 2-Cyano-2-phenyl-butyric Acid Ethyl Ester, 2-Phenyl-2-Ethyl-2-Cyanoacetic Acid Ethyl Ester, Benzeneacetic acid, α-cyano-α-ethyl-, ethyl ester, Butyric acid, 2-cyano-2-phenyl-, ethyl ester, Ethyl 2-Cyano-2-Phenylbutanoate, Ethyl 2-Phenyl-2-cyanobutyl acid ester, Ethyl Cyanoethylphenylacetate, Ethyl Ethylphenylcyanoacetate, Ethyl α-cyano-α-ethylbenzeneacetate, Ethylphenylcyano-Acetic Acid Ethyl Ester, NSC 69121, Nsc 6912, a-Cyano-a-ethyl-benzeneacetic Acid Ethyl Ester, Ethyl 2-Phenyl-2-Cyanobutylate

Description

Ethyl cyanoethylphenylacetate is an organophosphorus compound that is used as a solvent. It is insoluble in water, but soluble in organic solvents such as alcohols, ethers, and esters. Ethyl cyanoethylphenylacetate has been shown to react with sodium carbonate or diethyl carbonate to form the corresponding sodium or diethyl ester. This reaction can be used for the preparation of hexamidine and phenobarbital, which are important drugs for the treatment of tuberculosis and epilepsy. The scheme shown below illustrates the synthesis of hexamidine from ethyl cyanoethylphenylacetate:

Ethyl cyanoethylphenylacetate + NaHCO3 → NaC6H5OC(O)CH2CH2OC(O)CH2COONa + H2O

NaC6H5OC(O)CH2CH2OC(O)CH

• Brand: Biosynth

Chemical properties

• Molecular weight: 217.26 g/mol
• Formula: C₁₃H₁₅NO₂
• Purity: Min. 95%
• SMILES: CCOC(=O)C(C#N)(CC)c1ccccc1