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(R)-(-)-Etodolac
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(R)-(-)-Etodolac

CAS: 87226-41-3

Ref. 3D-FE23193

1mgDiscontinued
2mgDiscontinued
5mgDiscontinued
10mgDiscontinued
25mgDiscontinued

Discontinued product. For inquiries about similar products, please fill out our form or email us at .


Product Information

Name:
(R)-(-)-Etodolac
Synonyms:
  • (1R)-1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid(-)-(R)-Etodolac(-)-Etodolac
  • (1R)-1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid
  • (-)-Etodolic acid
  • R-Etodolac
  • Pyrano[3,4-b]indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-, (1R)-
  • Pyrano[3,4-b]indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-, (R)-
Description:

Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that inhibits prostaglandin synthesis. It also has a pro-apoptotic effect on cells and can induce apoptosis in primary cells. Etodolac is used to treat pain and inflammation associated with osteoarthritis and rheumatoid arthritis. The mechanism of action of etodolac is not fully understood, but it has been shown to inhibit the production of pro-inflammatory substances such as β-catenin and nitric oxide, which may be due to its ability to form an intermolecular hydrogen bond between the hydroxyl group on the drug molecule and the COX-2 inhibitory site on these enzymes.
Etodolac also binds to erythrocytes, resulting in a decreased blood flow rate in rats with induced inflammation. Etodolac has been shown to have an activity index of 150 compared with 10 for ibuprofen

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
287.35 g/mol
Formula:
C17H21NO3
Purity:
Min. 95%
InChI:
InChI=1S/C17H21NO3/c1-3-11-6-5-7-12-13-8-9-21-17(4-2,10-14(19)20)16(13)18-15(11)12/h5-7,18H,3-4,8-10H2,1-2H3,(H,19,20)/t17-/m1/s1
InChI key:
InChIKey=NNYBQONXHNTVIJ-QGZVFWFLSA-N
SMILES:
CCc1cccc2c3c([nH]c12)[C@@](CC)(CC(=O)O)OCC3
MDL:
Melting point:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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