Ethyl 2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-carboxylate

CAS: 148516-11-4

Ref. 3D-FE33201

Product Information

• Name: Ethyl 2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-carboxylate
• Synonyms: 2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinecarboxylic acid ethyl ester, Ethyl 2-Cyclopropyl-4-(4-Fluorophenyl)Quinoline-3-Carboxylate, N-1 Ethyl-2-Cyclopropyl-4-(4-Fluorophenyl)-Quinolyl-3- Carboxylate, 3-Quinolinecarboxylic acid,2-cyclopropyl-4-(4-fluorophenyl)-,ethyl ester

Description

Ethyl 2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-carboxylate is a lactonization inhibitor. It inhibits the activity of reductase, an enzyme that is involved in the biosynthesis of cholesterol. Ethyl 2-cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-carboxylate can be used to treat hypercholesterolemia and atherosclerosis by inhibiting the production of cholesterol. This product can also be used as a calcium salt to lower serum levels of triglycerides and increase HDL levels in patients with familial hypertriglyceridemia type I. This compound undergoes hydrolysis to form pitavastatin calcium, which is a phosphorus salt.

• Brand: Biosynth

Chemical properties

• Molecular weight: 335.37 g/mol
• Formula: C₂₁H₁₈FNO₂
• Purity: Min. 95%
• InChI: InChI=1S/C21H18FNO2/c1-2-25-21(24)19-18(13-9-11-15(22)12-10-13)16-5-3-4-6-17(16)23-20(19)14-7-8-14/h3-6,9-12,14H,2,7-8H2,1H3
• InChI key: InChIKey=GBRCWXJKFLLFPV-UHFFFAOYSA-N
• SMILES: CCOC(=O)c1c(C2CC2)nc2ccccc2c1-c1ccc(F)cc1