Ethyl 2-(2-aminothiazol-4-yl)-2-methoxyiminoacetate,predominantly syn

CAS: 64485-88-7

Ref. 3D-FE33499

Product Information

• Name: Ethyl 2-(2-aminothiazol-4-yl)-2-methoxyiminoacetate,predominantly syn
• Synonyms: 2-(2-Amino-4-thiazolyl)-2(Z)(methoxy)imino ethyl acetate, 4-Thiazoleacetic Acid, 2-Amino-Alpha-(Methoxyimino)-, Ethyl Ester, 4-Thiazoleacetic acid, 2-amino-α-(methoxyimino)-, ethyl ester, (Z)-, 4-Thiazoleacetic acid, 2-amino-α-(methoxyimino)-, ethyl ester, (αZ)-, 4-thiazoleacetic acid, 2-amino-alpha-(methoxyimino)-, ethyl ester, (AZ)-, Ethyl (Z)-(2-aminothiazol-4-yl)-α-methoxyiminoacetate, Ethyl (Z)-2-(2-Amino-4-Thiazolyl)-2-Methoxyiminoacetate, Ethyl (Z)-2-amino-alpha-(methoxyimino)thiazol-4-acetate, Ethyl (Z)-[2-amino-4-thiazolyl](methoxyimino)acetate, Ethyl (αZ)-2-amino-α-(methoxyimino)-4-thiazoleacetate, Ethyl 2-(2-aminothiazol-4-yl)-(Z)-2-(methoxyimino)acetate, Ethyl 2-(2-aminothiazol-4-yl)-2-methoxyiminoacetate, Ethyl 2-Amino-Alpha-(Methoxyimino)Thiazol-4-Acetate, Ethyl 2-Amino-alpha-(methoxyimino)-4-thiazoleacetate, Ethyl 2-Amino-Α-(Methoxyimino)Thiazol-4-Acetate, Ethyl-2-Methoxy-Amino-2-(2-Amino-Thiazole-4-Yl) Acetate, ethyl (2E)-(2-amino-1,3-thiazol-4-yl)(methoxyimino)ethanoate, ethyl (2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-acetate

Description

Ethyl 2-(2-aminothiazol-4-yl)-2-methoxyiminoacetate, predominately syn (AMT) is a synthetic drug that has been synthesized by the reaction of ethyl 2-(2-thiazolyl)-2-methoxyiminoacetate and 7-aminocephalosporanic acid. It is an acylase inhibitor and is used in the treatment of lysosomal storage diseases. AMT inhibits the enzyme α -1,4 glucosidase, which breaks down glycogen in the lysosomes. This inhibition leads to increased levels of glycogen in the lysosomes, which can then be broken down by other enzymes and catabolized for energy. AMT also inhibits other enzymes including acetoacetate decarboxylase, succinic semialdehyde dehydrogenase, and malic acid oxidoreductase. The drug's mechanism of action is thought

• Brand: Biosynth

Chemical properties

• Molecular weight: 229.26 g/mol
• Formula: C₈H₁₁N₃O₃S
• Purity: Min. 95%
• InChI: InChI=1S/C8H11N3O3S/c1-3-14-7(12)6(11-13-2)5-4-15-8(9)10-5/h4H,3H2,1-2H3,(H2,9,10)/b11-6-
• InChI key: InChIKey=POBMBNPEUPDXRS-WDZFZDKYSA-N
• SMILES: CCOC(=O)/C(=N\OC)c1csc(N)n1