Ethyl 3-chloroquinoxaline-2-carboxylate
CAS: 49679-45-0
Ref. 3D-FE44107
1g | To inquire | ||
5g | To inquire | ||
500mg | To inquire |
Product Information
- 2-Quinoxalinecarboxylic acid, 3-chloro-, ethyl ester
- Ethyl 3-chloroquinoxaline-2-carboxylate
Ethyl 3-chloroquinoxaline-2-carboxylate is a novel and selective inhibitor of the kinase Pim-1. It inhibits the enzymatic activity of Pim-1 at nanomolar concentrations, but does not inhibit other kinases such as Raf, Src, JNK, or ERK. Ethyl 3-chloroquinoxaline-2-carboxylate has been shown to be cytostatic in vitro at low micromolar concentrations against chronic myeloid leukemia cells. This drug also has an effect on tumor growth in vivo with no significant toxicity.
Chemical properties
Technical inquiry about: 3D-FE44107 Ethyl 3-chloroquinoxaline-2-carboxylate
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