Ethyl 5-methoxyindole-2-carboxylate

CAS: 4792-58-9

Ref. 3D-FE56797

Product Information

• Name: Ethyl 5-methoxyindole-2-carboxylate
• Synonyms: 2-Carbethoxy-5-methoxyindole5-Methoxy-1H-indole-2-carboxylic acid ethyl ester, 1H-Indole-2-carboxylic acid, 5-methoxy-, ethyl ester, 2-Carbethoxy-5-methoxyindole, 2-Ethoxycarbonyl-5-methoxyindole, 5-Methoxy-2-carbethoxyindole, Ethyl 5-methoxy-1H-indole-2-carboxylate, Ethyl 5-methoxy-2,3-1H-indole-2-carboxylate, Indole-2-carboxylic acid, 5-methoxy-, ethyl ester, Methoxy-5 indole carboxylate d'ethyle-2, NSC 30929

Description

Ethyl 5-methoxyindole-2-carboxylate (EMIC) is a derivative of the antibiotic mitomycin. EMIC inhibits bacterial growth by binding to the 50S ribosomal subunit and preventing protein synthesis. It has been shown to be active against gram-positive bacteria such as Staphylococcus aureus, Streptococcus pyogenes, and Bacillus subtilis. This drug also exhibits antibacterial activity against gram-negative bacteria such as Escherichia coli and Salmonella typhimurium. EMIC is an analogue of mitomycin C, which can be used in place of this drug for certain treatments.

• Brand: Biosynth

Chemical properties

• Molecular weight: 219.24 g/mol
• Formula: C₁₂H₁₃NO₃
• Purity: Min. 95%
• InChI: InChI=1S/C12H13NO3/c1-3-16-12(14)11-7-8-6-9(15-2)4-5-10(8)13-11/h4-7,13H,3H2,1-2H3
• InChI key: InChIKey=NPIUAXNFAUGNHP-UHFFFAOYSA-N
• SMILES: CCOC(=O)c1cc2cc(OC)ccc2[nH]1