Ethyl 2-amino-4-phenylthiazole-5-carboxylate

CAS: 64399-23-1

Ref. 3D-FE57154

Product Information

• Name: Ethyl 2-amino-4-phenylthiazole-5-carboxylate
• Synonyms: 2-Amino-4-phenylthiazole-5-carboxylic acid ethyl ester, 5-Thiazolecarboxylic acid, 2-amino-4-phenyl-, ethyl ester, Ethyl 2-amino-4-phenyl-5-thiazolecarboxylate, Nsc 119931, Ethyl 2-Amino-4-Phenyl-1,3-Thiazole-5-Carboxylate

Description

Ethyl 2-amino-4-phenylthiazole-5-carboxylate is a nitrogenous heterocyclic compound. It has been shown to have antileukaemic activity and can be used as an antineoplastic agent. The IC50 values of ethyl 2-amino-4-phenylthiazole-5-carboxylate for human cells are in the range of 0.3-2.0 μM, depending on the cell type and exposure time. It inhibits protein synthesis by binding to ribosomal RNA. This drug also has a toxicological effect on human cells, which may be due to its ability to induce conductivity changes or inhibit cellular metabolism.

• Brand: Biosynth

Chemical properties

• Molecular weight: 248.3 g/mol
• Formula: C₁₂H₁₂N₂O₂S
• Purity: Min. 95%
• InChI: InChI=1S/C12H12N2O2S/c1-2-16-11(15)10-9(14-12(13)17-10)8-6-4-3-5-7-8/h3-7H,2H2,1H3,(H2,13,14)
• InChI key: InChIKey=OZMXFXOHCUEEPD-UHFFFAOYSA-N
• SMILES: CCOC(=O)c1sc(N)nc1-c1ccccc1