Estra-1,3,5(10),6-tetraene-3,17-diol

CAS: 7291-41-0

Ref. 3D-FE59521

Product Information

• Name: Estra-1,3,5(10),6-tetraene-3,17-diol
• Synonyms: (17Beta)-Estra-1(10),2,4,6-Tetraene-3,17-Diol, (17β)-Estra-1,3,5(10),6-tetraene-3,17-diol, 6-Dehydroestradiol, Estra-1(10),2,4,6-Tetraene-3,17-Diol, (17Beta)-, Estra-1,3,5(10),6-tetraen-3,17beta-diol, Estra-1,3,5(10),6-tetraene-3,17-diol, (17.beta.)-, Estra-1,3,5(10),6-tetraene-3,17-diol, (17beta)-, Estra-1,3,5(10),6-tetraene-3,17-diol, (17β)-, Estra-1,3,5(10),6-tetraene-3,17β-diol, Estra-1,3,5(10)-6-tetraen-3,17β-diol, NSC 57430, Δ^6,7-Estradiol, Δ6,7-Estradiol

Description

Estra-1,3,5(10),6-tetraene-3,17-diol is a sulfonated derivative of estradiol. It is used as a ligand in binding assays to measure the affinity of various compounds for estrogens. Estra-1,3,5(10),6-tetraene-3,17-diol binds with high affinity to 17β-estradiol and other estrogens at the estrogen receptor. The binding of estradiol and its derivatives to the receptor leads to a conformational change that causes dissociation of heat shock proteins from the receptor. This results in an increase in transcriptional activity of the receptor and increased synthesis of mRNA.

• Brand: Biosynth

Chemical properties

• Molecular weight: 270.37 g/mol
• Formula: C₁₈H₂₂O₂
• Purity: Min. 95%