Ethyl 4-bromobenzoate

CAS: 5798-75-4

Ref. 3D-FE70444

Product Information

• Name: Ethyl 4-bromobenzoate
• Synonyms: 4-(Ethoxycarbonyl)-1-bromobenzene, 4-Bromobenzoic acid ethyl ester, 4-Carbethoxyphenyl bromide, Benzoic acid, 4-bromo-, ethyl ester, Benzoic acid, p-bromo-, ethyl ester, Ethyl 4-bromobenzoate, (4-Bromobenzoic acid ethyl ester), Ethyl p-bromobenzoate, NSC 67387, p-(Ethoxycarbonyl)phenyl bromide, p-Bromobenzoic acid ethyl ester
• CAS: 5798-75-4

Description

Ethyl 4-bromobenzoate is a halide that can be synthesized by the cross-coupling reaction with an aryl halide and a boronic acid. This synthesis has been used successfully to prepare benzoates, which are generally more difficult to synthesize than boronic acids. The coupling reaction of ethyl 4-bromobenzoate with an aryl halide and a boronic acid in the presence of copper as catalyst yields ethyl 4-bromobenzoate in high yield. A synergistic interaction occurs between the two reagents, leading to significant cytotoxicity in vitro. This property may be due to the light emission from this compound when it is exposed to ultraviolet light. Ethyl 4-bromobenzoate is also able to inhibit aerobic glycolysis and cancer cell growth in vitro through its ability to inhibit the activity of phosphofructokinase 1 (PFK1

• Brand: Biosynth

Chemical properties

• Molecular weight: 229.07 g/mol
• Formula: C₉H₉BrO₂
• Purity: Min. 97.5 Area-%
• Color/Form: Clear Liquid