Ethyl 2-tolylacetate

CAS: 40291-39-2

Ref. 3D-FE70962

Product Information

• Name: Ethyl 2-tolylacetate
• Synonyms: Ethyl 2-methylphenyl acetate, Acetic acid, o-tolyl-, ethyl ester, Benzeneacetic acid, 2-methyl-, ethyl ester, Ethyl (2-Methylphenyl)Acetate, Ethyl 2-methylbenzeneacetate, NSC 78459, o-Tolylacetic acid ethyl ester
• CAS: 40291-39-2

Description

Ethyl 2-tolylacetate is a colorless liquid with a fruity odor. It is used as an intermediate in the synthesis of other organic compounds, such as pharmaceuticals and agrochemicals. This compound can be prepared by the reductive coupling of ethyl bromoacetate with toluene via palladium catalysis or by the cross-coupling of ethyl bromoacetate with 2-chloropropiophenone. The regiospecificity of this reaction was found to depend on the nature of the nucleophile and the boronic acid used in the reaction. Ethyl 2-tolylacetate is also used for peptide synthesis and as an ligand for sulphoxides.

• Brand: Biosynth

Chemical properties

• Molecular weight: 178.23 g/mol
• Formula: C₁₁H₁₄O₂
• Purity: Min. 95%
• Color/Form: Clear Liquid
• InChI: InChI=1S/C11H14O2/c1-3-13-11(12)8-10-7-5-4-6-9(10)2/h4-7H,3,8H2,1-2H3
• InChI key: InChIKey=HTDQOYWJDUMNHX-UHFFFAOYSA-N
• SMILES: CCOC(=O)Cc1ccccc1C