Product Information
- Benzonitrile, 2-ethynyl-
2-Ethynylbenzonitrile is a nitrogenous compound that contains an azide group. It forms the nitrate salt in water, which is highly soluble in organic solvents. 2-Ethynylbenzonitrile has been shown to be a potent inhibitor of topoisomerase I and II, with IC50 values of 0.5 and 4 μM respectively. This compound has also been shown to induce apoptosis in cancer cells and act as a stabilizer of DNA at high temperatures. The inhibition of topoisomerase I and II by 2-ethynylbenzonitrile is analogous to that of anthracyclines and daunomycin.
Chemical properties
Technical inquiry about: 3D-FE74609 2-ethynylbenzonitrile
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