5-Fluoro-1-(tetrahydro-2-furyl)uracil

CAS: 17902-23-7

Ref. 3D-FF08013

Product Information

• Name: 5-Fluoro-1-(tetrahydro-2-furyl)uracil
• Synonyms: FtorafurTegafur, 1-(2'-Tetrahydrofuryl)-5-fluorouracil, 1-(Tetrahydro-2-furanyl)-5-fluoro-2,4-pyrimidinedione, 1-(Tetrahydro-2-furanyl)-5-fluorouracil, 1-Naphthol-3,8-Disulfonic Acid, 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-(tetrahydro-2-furanyl)-, 5-Fluor-1-(tetrahydro-2-furyl)uracil, 5-Fluoro-1-(2-tetrahydrofuranyl)uracil, 5-Fluoro-1-(Tetrahidro-2-Furil)Uracilo, 5-Fluoro-1-(Tetrahydrofuran-2-Yl)Uracil, 5-Fluoro-1-(tetrahydro-2-furanyl)-2,4(1H,3H)-pyrimidinedione, 5-Fluoro-1-(tetrahydro-2-furanyl)-2,4-pyrimidinedione, 5-Fluoro-1-(tetrahydro-2-furfuryl)uracil, 5-Fluoro-1-(tetrahydro-2-furyl)uracile, 5-Fluoro-1-Oxolan-2-Yl-Pyrimidine-2,4-Dione, 5-fluoro-1-(tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione, 5-fluoro-1-[(2R)-tetrahydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione, Citofur, Coparogin, Epsilone Acid, Exonal, Fental, Fluaid, Fluorafur, Fluorofur, Franrose, Ft 207, Fulaid, Fulfeel, Furafluor, Furofutran, Futraful, Lamar, Lifril, Mjf 12264, N1-(2'-Tetrahydrofuryl)-5-fluorouracil, N1-(2-Tetrahydrofuranyl)-5-fluorouracil, N¹-(2-Tetrahydrofuranyl)-5-fluorouracil, N¹-(2-Tetrahydrofuryl)-5-fluorouracil, Neberk, Nitobanil, Nsc 148-958, Nsc 148958, Racemic Ftorafur, Riol, Sinoflurol, Sunfural, Tefsiel C, Tegafur, Ts 1, Uracil, 5-fluoro-1-(tetrahydro-2-furyl)-, Utefos
• CAS: 17902-23-7

Description

5-Fluoro-1-(tetrahydro-2-furyl)uracil (5FU) is an oral prodrug that is converted to 5-fluorouracil in the body. 5FU has been shown to be a chemotherapeutic agent, which inhibits cancer cell growth by inhibiting DNA synthesis and RNA synthesis. It also induces apoptosis in cancer cells and has synergistic effects with other drugs such as tegafur, which inhibits the enzyme uridine diphosphate (UDP) glucuronosyltransferase. This combination therapy group has been shown to be effective against tumors of the colon, breast, and head and neck.

• Brand: Biosynth

Chemical properties

• Molecular weight: 200.17 g/mol
• Formula: C₈H₉FN₂O₃
• Purity: Min. 95%
• Color/Form: White Powder