10-Fluoro-7-Thiophen-2-Yl-1,2,3,4,4a,5-Hexahydropyrazino[1,2-a][1,4]Benzodiazepine

CAS: 110622-75-8

Ref. 3D-FF100874

Product Information

• Name: 10-Fluoro-7-Thiophen-2-Yl-1,2,3,4,4a,5-Hexahydropyrazino[1,2-a][1,4]Benzodiazepine
• Synonyms: 10-Fluoro-1,2,3,4,4a,5-hexahydro-7-(2-thienyl)pyrazino(1,2-a)(1,4)benzodiazepine, Kc 8122, N-Demethyltimelotem, Pyrazino(1,2-a)(1,4)benzodiazepine, 10-fluoro-1,2,3,4,4a,5-hexahydro-7-(2-thienyl)-, 10-Fluoro-7-(Thiophen-2-Yl)-1,2,3,4,4A,5-Hexahydropyrazino[1,2-A][1,4]Benzodiazepine

Description

10-Fluoro-7-thiophen-2-yl-1,2,3,4,4a,5-hexahydropyrazino[1,2-a][1,4]benzodiazepine (10FT) is a metabolite of the anti-seizure drug levetiracetam. 10FT has been shown to be a substrate for neural metabolism and an inhibitor of neuronal acetylcholine release. 10FT is also a potent competitive antagonist at the benzodiazepine binding site on the gamma subunit of the GABAA receptor in rat brain membranes. 10FT is devoid of any detectable anticonvulsant activity and does not bind to benzodiazepine receptors in mice.

• Brand: Biosynth

Chemical properties

• Molecular weight: 301.38 g/mol
• Formula: C₁₆H₁₆FN₃S
• Purity: Min. 95%
• InChI: InChI=1S/C16H16FN3S/c17-11-3-4-13-14(8-11)20-6-5-18-9-12(20)10-19-16(13)15-2-1-7-21-15/h1-4,7-8,12,18H,5-6,9-10H2
• InChI key: InChIKey=PVYHRFIWKKDZDL-UHFFFAOYSA-N
• SMILES: Fc1ccc2c(c1)N1CCNCC1CN=C2c1cccs1