6-Fluoro-9-Methyl-2-Phenyl-4-(1-Pyrrolidinylcarbonyl)-2,9-Dihydro-1H-β-Carbolin-1-One
CAS: 205881-86-3
Ref. 3D-FF101536
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Product Information
- 1H-Pyrido[3,4-b]indol-1-one, 6-fluoro-2,9-dihydro-9-methyl-2-phenyl-4-(1-pyrrolidinylcarbonyl)-
- 6-Fluoro-2,9-dihydro-9-methyl-2-phenyl-4-(1-pyrrolidinylcarbonyl)-1H-pyrido[3,4-b]indol-1-one
- Pyrrolidine, 1-[(6-fluoro-2,9-dihydro-9-methyl-1-oxo-2-phenyl-1H-pyrido[3,4-b]indol-4-yl)carbonyl]-
- Sl-65.1498
- Sl-651498
6-Fluoro-9-Methyl-2-Phenyl-4-(1-pyrrolidinylcarbonyl)-2,9-Dihydro-1H-beta-Carbolin-1 One (FMOC) is a specific antidote for the treatment of poisoning with organophosphorus compounds. It is a competitive antagonist of the nicotinic acetylcholine receptor in synapses and competitive antagonist of gamma aminobutyric acid (GABA) at GABA receptors. FMOC binds to the benzodiazepine binding site on the GABAA receptor and causes convulsions. FMOC also has allosteric modulator activity, which may be due to its ability to bind to benzodiazepine binding sites on neuronal membranes, which are not selective for GABA over other neurotransmitters.
Chemical properties
Technical inquiry about: 3D-FF101536 6-Fluoro-9-Methyl-2-Phenyl-4-(1-Pyrrolidinylcarbonyl)-2,9-Dihydro-1H-β-Carbolin-1-One
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