5-[(3S,4R,5R)-3-Fluoro-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-1-Methylpyrimidine-2,4-Dione
CAS: 110419-25-5
Ref. 3D-FF101794
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Product Information
- 5-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-1-methyl-2,4(1H,3H)-pyrimidinedione
- 5-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-1-methyluracil
- 2,4(1H,3H)-Pyrimidinedione, 5-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-1-methyl-
- (1xi)-1,4-anhydro-2-deoxy-2-fluoro-1-(1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-arabinitol
5-[(3S,4R,5R)-3-Fluoro-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-1-Methylpyrimidine-2,4-Dione is a nucleoside analog that inhibits the replication of influenza A virus. It has been shown to have significant inhibitory activity against influenza A and B viruses in tissue culture. 5-[(3S,4R,5R)-3-Fluoro-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-1-Methylpyrimidine-2,4-Dione inhibits the uptake of influenza virus by cells. This drug is a nucleophilic agent that reacts with azides to form an azide intermediate. The azide intermediate then reacts with sulfur trifluoride to produce pyrimidine sulfonyl fluoride and difluoroamine.
Chemical properties
Technical inquiry about: 3D-FF101794 5-[(3S,4R,5R)-3-Fluoro-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-1-Methylpyrimidine-2,4-Dione
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