8-[4-(4-Fluorophenyl)-4-Oxobutyl]-3-(2-Iodoethyl)-1-Phenyl-1,3,8-Triazaspiro[4.5]Decan-4-One
CAS: 130482-21-2
Ref. 3D-FF101876
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Product Information
- 125I-Ies
- 8-(4-(4-Fluorophenyl)-4-oxobutyl)-1-phenyl-3-(2-iodoethyl)-1,3,8-triazaspiro(4,5)decan-4-one
- 8-(4-(4-Fluorophenyl)-4-oxobutyl)-3-(2-(iodo-125I)ethyl)-1-phenyl-1,3,8-triazaspiro(4.5)decan-4-one
- 1,3,8-Triazaspiro(4.5)decan-4-one, 8-(4-(4-fluorophenyl)-4-oxobutyl)-3-(2-(iodo-125I)ethyl)-1-phenyl-
8-[4-(4-Fluorophenyl)-4-Oxobutyl]-3-(2-Iodoethyl)-1-Phenyl-1,3,8-Triazaspiro[4.5]Decan-4-One is a ligand that binds to the dopamine D2 receptor with high affinity. It has been shown to be useful in treating Parkinson's disease and related disorders by blocking the uptake of dopamine, which leads to increased dopamine concentrations in the brain. This agent is also used as a radioligand for autoradiography studies of dopaminergic pathways in vivo and can be modified with conjugates such as fatty acids for use in positron emission tomography (PET) imaging. 8-[4-(4-Fluorophenyl)-4-Oxobutyl]-3-(2-Iodoethyl)-1-Phenyl-1,3,8-Triazaspiro[4.5]Dec
Chemical properties
Technical inquiry about: 3D-FF101876 8-[4-(4-Fluorophenyl)-4-Oxobutyl]-3-(2-Iodoethyl)-1-Phenyl-1,3,8-Triazaspiro[4.5]Decan-4-One
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