![5-Fluoro-2,4-Dioxo-N-[6-[[2-(2-Propylpentanoylamino)Acetyl]Amino]Hexyl]Pyrimidine-1-Carboxamide](https://static.cymitquimica.com/products/3D/img/FF102106.png "Click to enlarge")
5-Fluoro-2,4-Dioxo-N-[6-[[2-(2-Propylpentanoylamino)Acetyl]Amino]Hexyl]Pyrimidine-1-Carboxamide
CAS: 134460-39-2
Ref. 3D-FF102106
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Product Information
- 1-(6-(N-(2-n-Propyl-n-pentanoyl)glycyl)amino-n-hexylcarbamoyl)-5-fluorouracil
- 1(2H)-Pyrimidinecarboxamide, 5-fluoro-3,4-dihydro-2,4-dioxo-N-(6-((((1-oxo-2-propylpentyl)amino)acetyl)amino)hexyl)-
- 5-fluoro-2,4-dioxo-N-(6-{[N-(2-propylpentanoyl)glycyl]amino}hexyl)-3,4-dihydropyrimidine-1(2H)-carboxamide
- UK-25
5-Fluoro-2,4-Dioxo-N-[6-[[2-(2-Propylpentanoylamino)Acetyl]Amino]Hexyl]Pyrimidine-1-Carboxamide is a potent antitumor agent that has been shown to inhibit tumor growth in mice. It is an inhibitor of the enzyme DNA polymerase alpha, which is involved in the synthesis of DNA. This inhibition leads to DNA replication errors and cell death. 5FDAPC has been shown to have antiangiogenic effects on the tumor vasculature, leading to reduced oxygen and nutrient supply. The compound has also been shown to be active against a broad range of organisms, including gram positive and gram negative bacteria. A number of techniques have been used to study 5FDAPC, including sequencing techniques, modelling studies, and type species analysis. The compound is unstable in plasma samples due to hydrolysis by plasma enzymes such as amin
Chemical properties
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