[(2R,3R,4R,5R)-5-(5-Fluoro-2,4-Dioxo-Pyrimidin-1-Yl)-3,4-Dihydroxy-Oxolan-2-Yl]Methyl Octanoate

CAS: 118694-10-3

Ref. 3D-FF102110

Product Information

• Name: [(2R,3R,4R,5R)-5-(5-Fluoro-2,4-Dioxo-Pyrimidin-1-Yl)-3,4-Dihydroxy-Oxolan-2-Yl]Methyl Octanoate
• Synonyms: 5'-Octanoyl-5-Fluoro-2'-Deoxyuridine, 5-fluoro-5'-O-octanoyluridine

Description

[(2R,3R,4R,5R)-5-(5-Fluoro-2,4-Dioxo-Pyrimidin-1-Yl) -3,4-Dihydroxy-Oxolan-2-Yl]Methyl Octanoate is a prodrug that is hydrolyzed in the human body to form 5-[(2R,3R,4R,5R)-3-(2,6-dichlorophenyl) -5-(hydroxymethyl)-4-(methyloxy)oxolan-2-yl]-2,4,-dioxopyrimidine. It has been shown to be an effective agent for the treatment of sarcomas and other cancers. The lipiodol component of this prodrug is used as a contrast agent for lymphography. This product can also be used as a protein stabilizer in bovine and porcine liver preparations.

• Brand: Biosynth

Chemical properties

• Molecular weight: 388.39 g/mol
• Formula: C₁₇H₂₅FN₂O₇
• Purity: Min. 95%
• InChI: InChI=1S/C17H25FN2O7/c1-2-3-4-5-6-7-12(21)26-9-11-13(22)14(23)16(27-11)20-8-10(18)15(24)19-17(20)25/h8,11,13-14,16,22-23H,2-7,9H2,1H3,(H,19,24,25)/t11-,13-,14-,16-/m1/s1
• InChI key: InChIKey=UPKOVIISKGPRGG-XKVFNRALSA-N
• SMILES: CCCCCCCC(=O)OC[C@H]1O[C@@H](n2cc(F)c(=O)[nH]c2=O)[C@H](O)[C@@H]1O