N-(1-(2-Fluorophenyl)-3,4,6,7-tetrahydro-4-oxo-pyrrolo(3,2,1-jk)(1,4)benzodiazepin-3-yl)-1H-indole-2-carboxamide

CAS: 150408-73-4

Ref. 3D-FF103082

Product Information

• Name: N-(1-(2-Fluorophenyl)-3,4,6,7-tetrahydro-4-oxo-pyrrolo(3,2,1-jk)(1,4)benzodiazepin-3-yl)-1H-indole-2-carboxamide
• Synonyms: 1H-Indole-2-carboxamide, N-[(3S)-1-(2-fluorophenyl)-3,4,6,7-tetrahydro-4-oxopyrrolo[3,2,1-jk][1,4]benzodiazepin-3-yl]-, 1H-Indole-2-carboxamide, N-[1-(2-fluorophenyl)-3,4,6,7-tetrahydro-4-oxopyrrolo[3,2,1-jk][1,4]benzodiazepin-3-yl]-, (S)-, Fk 480, Fr 120480, N-[(3S)-1-(2-Fluorophenyl)-3,4,6,7-tetrahydro-4-oxopyrrolo[3,2,1-jk][1,4]benzodiazepin-3-yl]-1H-indole-2-carboxamide, N-[(3S)-1-(2-fluorophenyl)-4-oxo-3,4,6,7-tetrahydro[1,4]diazepino[6,7,1-hi]indol-3-yl]-1H-indole-2-carboxamide, Pyrrolo[3,2,1-jk][1,4]benzodiazepine, 1H-indole-2-carboxamide deriv.

Description

N-(1-(2-Fluorophenyl)-3,4,6,7-tetrahydro-4-oxo-pyrrolo(3,2,1-jk)(1,4)benzodiazepin-3-yl)-1H-indole-2-carboxamide is a potent and specific inhibitor of voltage dependent calcium channels. It has been shown to have effects on pancreatic cells in vivo. N-(1-(2-Fluorophenyl)-3,4,6,7-tetrahydro-4-oxo pyrrolo(3,2,1,-jk)(1,4)benzodiazepin--3 yl)-1H indole 2 carboxamide is a chiral compound with two enantiomers. The drug inhibits the pancreatic enzyme trypsin and may cause liver damage by forming hydrochloric acid. It also has the potential

• Brand: Biosynth

Chemical properties

• Molecular weight: 438.45 g/mol
• Formula: C₂₆H₁₉FN₄O₂
• Purity: Min. 95%
• InChI: InChI=1S/C26H19FN4O2/c27-19-10-3-2-8-17(19)22-18-9-5-7-15-12-13-31(23(15)18)26(33)24(29-22)30-25(32)21-14-16-6-1-4-11-20(16)28-21/h1-11,14,24,28H,12-13H2,(H,30,32)/t24-/m1/s1
• InChI key: InChIKey=WKJDXKWFGJWGAS-XMMPIXPASA-N
• SMILES: O=C(N[C@H]1N=C(c2ccccc2F)c2cccc3c2N(CC3)C1=O)c1cc2ccccc2[nH]1