5-((Z)-(5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

CAS: 356068-93-4

Ref. 3D-FF106180

Product Information

• Name: 5-((Z)-(5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
• Synonyms: 1H-pyrrole-3-carboxylic acid, 5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-, 5-[(Z)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

Description

5-((Z)-(5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl is an inhibitor of protein kinase. It inhibits the activity of protein kinase C (PKC) and also has immunosuppressive properties. 5-(2,4-Dimethylphenyl)-5-[(5-fluoroindolinylidene)methyl]pyrrole is a white to off white crystalline powder that belongs to the class of pyrroles. It has been shown to be a vasotropic agent by binding to the alpha 1 beta 1 integrin receptor on vascular smooth muscle cells. This drug binds to aminophospholipids in plasma and can cause osteopathic lesions when injected into bone tissue. 5-(2,4-Dimethylphenyl)-5-[(5-fluoroindolinylidene)methyl]pyrrole has been shown to have antiinflammatory effects

• Brand: Biosynth

Chemical properties

• Molecular weight: 300.28 g/mol
• Formula: C₁₆H₁₃FN₂O₃
• Purity: Min. 95%
• InChI: InChI=1S/C16H13FN2O3/c1-7-13(18-8(2)14(7)16(21)22)6-11-10-5-9(17)3-4-12(10)19-15(11)20/h3-6,18H,1-2H3,(H,19,20)(H,21,22)/b11-6-
• InChI key: InChIKey=RBHBOUYXUXWCNJ-WDZFZDKYSA-N
• SMILES: Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)O