3-(2-Furyl)-1H-1,2,4-triazole-5-thiol

CAS: 35771-65-4

Ref. 3D-FF122965

Product Information

• Name: 3-(2-Furyl)-1H-1,2,4-triazole-5-thiol
• Synonyms: 1H-1,2,4-triazole-5-thiol, 3-(2-furanyl)-, 1-(furan-2-yl)-1,2-dihydro-3H-1,2,4-triazole-3-thione, 3-(2-Furyl)-1,2,4-triazole-5-thiol, 3-(2-Furyl)-5-mercapto-1,2,4-triazole, 3H-1,2,4-Triazole-3-thione, 5-(2-furanyl)-1,2-dihydro-, 5-(2-Furanyl)-1,2-dihydro-3H-1,2,4-triazole-3-thione, 5-(2-Furyl)-1,2,4-triazole-3-thione, 5-(furan-2-yl)-1,2-dihydro-3H-1,2,4-triazole-3-thione, s-Triazole-3-thiol, 5-(2-furyl)-, 5-Furyl-1,2-dihydro-3H-1,2,4-triazole-3-thione

Description

3-(2-Furyl)-1H-1,2,4-triazole-5-thiol is a chemical compound that inhibits the growth of bacteria by interfering with bacterial DNA replication. It has been shown to have antibacterial activity against gram-positive and gram-negative bacteria and Staphylococcus aureus. 3-(2-Furyl)-1H-1,2,4-triazole-5-thiol binds to the bacterial DNA gyrase enzyme and prevents the proper operation of this enzyme. This leads to inhibition of DNA synthesis and ultimately cell death. 3-(2-Furyl)-1H-1,2,4-triazole-5-thiol also has antiinflammatory properties.

• Brand: Biosynth

Chemical properties

• Molecular weight: 167.19 g/mol
• Formula: C₆H₅N₃OS
• Purity: Min. 95%
• InChI: InChI=1S/C6H5N3OS/c11-6-7-5(8-9-6)4-2-1-3-10-4/h1-3H,(H2,7,8,9,11)
• InChI key: InChIKey=PQFBWTHPDGFZBD-UHFFFAOYSA-N
• SMILES: S=c1nc(-c2ccco2)[nH][nH]1