4-Fluoro-a-oxo-benzeneacetaldehyde
CAS: 403-32-7
Ref. 3D-FF23492
| 1g | To inquire | ||
| 2g | To inquire | ||
| 5g | To inquire | ||
| 250mg | To inquire | ||
| 500mg | To inquire |
Product Information
- (4-Fluorophenyl)glyoxal(p-Fluorophenyl)glyoxal2-(4-Fluorophenyl)-2-oxoacetaldehyde
- (4-Fluorophenyl)(Oxo)Acetaldehyde
- (4-Fluorophenyl)(Oxo)Acetaldehyde Hydrate
- (4-Fluorophenyl)glyoxal
- (p-Fluorophenyl)glyoxal
- 2-(4-Fluorophenyl)-2-oxoacetaldehyde
- 4-Fluoro-alpha-oxobenzeneacetaldehyde
- 4-Fluoro-α-oxobenzeneacetaldehyde
- Benzeneacetaldehyde, 4-fluoro-alpha-oxo-
- Benzeneacetaldehyde, 4-fluoro-α-oxo-
- See more synonyms
- Brn 2354778
- Glyoxal, (p-fluorophenyl)-
- NSC 402742
4-Fluoro-a-oxo-benzeneacetaldehyde belongs to the class of triazolones and is a potent inhibitor of cytochrome P450 (CYP) 2C19. It has been shown that 4-fluoro-a-oxo-benzeneacetaldehyde is more potent than other compounds in this class, such as 6-(2,6-dichlorophenyl)-N-(2,2,2-trifluoroethyl)-4-(4′methylphenyl)-1,3,5 triazinone. The rat brain microsomes were used to assess the inhibitory activity of 4-fluoro-a-oxo benzeneacetaldehyde against CYP 2C19. This compound also inhibits recombinant human CYP 2C19. Treatment with 4FAA inhibited the formation of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate
Chemical properties
Technical inquiry about: 3D-FF23492 4-Fluoro-a-oxo-benzeneacetaldehyde
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