N-Fmoc-L-pipecolinic acid

CAS: 86069-86-5

Ref. 3D-FF29036

Product Information

• Name: N-Fmoc-L-pipecolinic acid
• Synonyms: 1,2-Piperidinedicarboxylicacid, 1-(9H-fluoren-9-ylmethyl) ester, (2S)-, 1,2-Piperidinedicarboxylicacid, 1-(9H-fluoren-9-ylmethyl) ester, (S)-, N-(9-Fluorenylmethoxycarbonyl)pipecolicacid, N-Fmoc-(2S)-piperidinecarboxylic acid, Fmoc-b-Homo-Pro-OH, Fmoc-L-Pipecolic Acid, Fmoc-HoPro-OH

Description

N-Fmoc-L-pipecolinic acid is a tripeptide that is an antagonist of oxytocin. It has been shown to have a high reactivity in the solid phase synthesis, and can be assembled on a solid support such as polystyrene via the Fmoc chemistry. The active ester is synthesized by reacting fmoc-l-pipecolic acid with acid chlorides in sequential steps. The reagents used are chloroacetic acid, N,O-dimethylhydroxylamine hydrochloride, and dimethylaminopyridine. This product also has a high reactivity with other acids such as hexapeptide.

• Brand: Biosynth

Chemical properties

• Molecular weight: 351.4 g/mol
• Formula: C₂₁H₂₁NO₄
• Purity: Min. 95%
• InChI: InChI=1S/C21H21NO4/c23-20(24)19-11-5-6-12-22(19)21(25)26-13-18-16-9-3-1-7-14(16)15-8-2-4-10-17(15)18/h1-4,7-10,18-19H,5-6,11-13H2,(H,23,24)/t19-/m0/s1
• InChI key: InChIKey=CKLAZLINARHOTG-IBGZPJMESA-N
• SMILES: O=C(O)[C@@H]1CCCCN1C(=O)OCC1c2ccccc2-c2ccccc21