6-Fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran

CAS: 99199-90-3

Ref. 3D-FF31339

Product Information

• Name: 6-Fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran
• Synonyms: 2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-(2-oxiranyl)-, 2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-oxiranyl-, 6-Fluoro-2-(oxiran-2-yl)chroman, 6-Fluoro-2-(oxiranyl)-3,4-dihydro-1-benzopyran, 6-Fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran, 6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene

Description

Nebivolol is a selective beta-1 receptor blocker that is used in the treatment of high blood pressure. It has been shown to be effective in the prevention and treatment of heart disease, including angina, myocardial infarction, and sudden cardiac death. Nebivolol is administered orally as a hydrochloride salt. The major impurities are esters of nebivolol such as dimethylsulfoxide and diastereomeric erythro- and threo-nebivolols. Nebivolol hydrochloride is an intermediate for other drugs with oral dosage forms such as c1-6 alkyl esters, structural analogues, heteroaryls.

• Brand: Biosynth

Chemical properties

• Molecular weight: 194.2 g/mol
• Formula: C₁₁H₁₁FO₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C11H11FO2/c12-8-2-4-9-7(5-8)1-3-10(14-9)11-6-13-11/h2,4-5,10-11H,1,3,6H2
• InChI key: InChIKey=GVZDIJGBXSDSEP-UHFFFAOYSA-N
• SMILES: Fc1ccc2c(c1)CCC(C1CO1)O2