2-Fluorocinnamic acid

CAS: 451-69-4

Ref. 3D-FF37093

Product Information

• Name: 2-Fluorocinnamic acid
• Synonyms: (2E)-3-(2-fluorophenyl)prop-2-enoate, 2-Propenoic acid, 3-(2-fluorophenyl)-, 3-(2-Fluorophenyl)-2-propenoic acid, 3-(2-Fluorophenyl)acrylic acid, 3-(2-Fluorophenyl)propenoic acid, Cinnamic acid, o-fluoro-, NSC 73989, o-Fluorocinnamic acid
• CAS: 451-69-4

Description

2-Fluorocinnamic acid is a cinnamic acid derivative that is used as an antibiotic. It has been shown to have bacteriostatic activity against a wide range of bacteria, including some strains of Staphylococcus and Streptococcus. 2-Fluorocinnamic acid binds to the enzyme that synthesizes amide and coumarin derivatives, thereby inhibiting its activity. This binding prevents the formation of bacterial cell wall and cell membrane components, leading to cell death. 2-Fluorocinnamic acid has also been used in the treatment of diabetic neuropathy. The drug interacts electronically with hydrogen fluoride (HF) and deionized water (DIW), with the rate of reaction increasing with pH. The reaction product is analyzed using high performance liquid chromatography (HPLC). 2-Fluorocinnamic acid inhibits bacterial growth by competing for substrate binding sites on enzymes such as β-lactamase, which are

• Brand: Biosynth

Chemical properties

• Molecular weight: 166.15 g/mol
• Formula: C₉H₇FO₂
• Purity: Min. 95%
• Color/Form: Powder