Fmoc-D-Trp-OH

CAS: 86123-11-7

Ref. 3D-FF37419

Product Information

• Name: Fmoc-D-Trp-OH
• Synonyms: N-alpha-(9-fluorenylmethoxycarbonyl)-D-tryptophan, (2R)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-(1H-indol-3-yl)propanoate
• CAS: 86123-11-7

Description

Fmoc-D-Trp-OH is a cinchonidine analog that is synthesized through the coupling of two amino acid molecules, D-Trp and Fmoc-Lys. This compound has been shown to have anti-cancer properties in tumor xenografts, which may be due to its ability to bind hydrogen bonding interactions with proteins. Fmoc-D-Trp-OH also has an anti-inflammatory effect on Alzheimer's disease and cancer cells, which could be due to its ability to inhibit immune cell recruitment and increase apoptosis rates. In addition, it can be used as an optical imaging agent for the detection of brain tumors.

• Brand: Biosynth

Chemical properties

• Molecular weight: 426.46 g/mol
• Formula: C₂₆H₂₂N₂O₄
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C26H22N2O4/c29-25(30)24(13-16-14-27-23-12-6-5-7-17(16)23)28-26(31)32-15-22-20-10-3-1-8-18(20)19-9-2-4-11-21(19)22/h1-12,14,22,24,27H,13,15H2,(H,28,31)(H,29,30)/t24-/m1/s1
• InChI key: InChIKey=MGHMWKZOLAAOTD-XMMPIXPASA-N
• SMILES: O=C(N[C@H](Cc1c[nH]c2ccccc12)C(=O)O)OCC1c2ccccc2-c2ccccc21