Fmoc-D-gln-OH

CAS: 112898-00-7

Ref. 3D-FF39455

Product Information

• Name: Fmoc-D-gln-OH
• Synonyms: (2R)-5-Amino-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-oxopentanoic acid, 299: PN: US20070042401 PAGE: 38 claimed protein, 991: PN: WO2006135786 PAGE: 71 claimed protein, <span class="text-smallcaps">D</span>-Glutamine, N²-[(9H-fluoren-9-ylmethoxy)carbonyl]-, Fmoc-D-Gln-OH, N²-[(9H-Fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">D</span>-glutamine, N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-glutamine

Description

Fmoc-D-gln-OH is a hydrophobic amide that has bactericidal activity. It is an antibacterial agent that inhibits the growth of bacteria by binding to their cell walls and disrupting the cell membrane. Fmoc-D-gln-OH has been shown to be active against Staphylococcus, Propionibacterium, and Isosteres. This drug binds to the δ opioid receptor in bacteria and prevents them from synthesizing proteins required for cell wall biosynthesis, leading to cell death. Fmoc-D-gln-OH also has macrocyclic substitutions that can be replaced with other amino acids with different properties. These substitutions are designed to make this drug more potent or have a longer half life.

• Brand: Biosynth

Chemical properties

• Molecular weight: 368.38 g/mol
• Formula: C₂₀H₂₀N₂O₅
• Purity: Min. 95%
• InChI: InChI=1S/C20H20N2O5/c21-18(23)10-9-17(19(24)25)22-20(26)27-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16-17H,9-11H2,(H2,21,23)(H,22,26)(H,24,25)/t17-/m1/s1
• InChI key: InChIKey=IZKGGDFLLNVXNZ-QGZVFWFLSA-N
• SMILES: NC(=O)CC[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O