(R)-4-Fluorophenylglycine

CAS: 93939-74-3

Ref. 3D-FF40731

Product Information

• Name: (R)-4-Fluorophenylglycine
• Synonyms: (2R)-2-Amino-2-(4-fluorophenyl)acetic acid, (2R)-2-Azaniumyl-2-(4-fluorophenyl)acetate, (R)-2-Amino-2-(4-fluorophenyl)acetic acid, (αR)-α-Amino-4-fluorobenzeneacetic acid, 4-Fluoro-<span class="text-smallcaps">D</span>-α-phenylglycine, 4-Fluoro-D-alpha-phenylglycine, 4-Fluoro-D-α-phenylglycine, <span class="text-smallcaps">D</span>-(-)-4-Fluorophenylglycine, Benzeneacetic acid, α-amino-4-fluoro-, (R)-, Benzeneacetic acid, α-amino-4-fluoro-, (αR)-, D-(4-fluorophenyl)glycine

Description

(R)-4-Fluorophenylglycine is a metabolic intermediate that is involved in the synthesis of dopamine. It has fusogenic properties, which allow it to act as a membrane-active agent and disrupt cell membranes. It also inhibits aminotransferases, dehydrogenases, and other enzymes that are involved in the synthesis of neurotransmitters. This compound has been shown to have antidyskinetic effects in animal models of Parkinson's disease. (R)-4-Fluorophenylglycine is used as an analog for dopamine in biological assays because it binds to striatal dopamine receptors and can cause similar responses to dopamine itself. The reaction time of animals given this drug was prolonged by 20% when compared with control animals. Trifluoroacetic acid was used as a solvent in these experiments because it will not react with (R)-4-fluorophenylglycine and will not interfere with any chemical reactions involving this

• Brand: Biosynth

Chemical properties

• Molecular weight: 169.15 g/mol
• Formula: C₈H₈FNO₂
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C8H8FNO2/c9-6-3-1-5(2-4-6)7(10)8(11)12/h1-4,7H,10H2,(H,11,12)/t7-/m1/s1
• InChI key: InChIKey=JKFYKCYQEWQPTM-SSDOTTSWSA-N
• SMILES: N[C@@H](C(=O)O)c1ccc(F)cc1