5-Fluoro-1,3-dihydrobenzoimidazol-2-one
CAS: 1544-75-8
Ref. 3D-FF41960
| 1g | To inquire | ||
| 250mg | To inquire | ||
| 500mg | To inquire |
Product Information
- 5-Fluorobenzimidazolone
- 2H-Benzimidazol-2-one,
- 5-fluoro-1,3-dihydro-
- 5-Fluoro-1,3-Dihydrobenzoimidazol-2-One
- 5-Fluoro-1H-benzo[d]imidazol-2(3H)-one
5-Fluoro-1,3-dihydrobenzoimidazol-2-one (5FDBI) is a potent antiproliferative compound that inhibits the proliferation of cancer cells. It has been shown to be a potent inhibitor of docetaxel and other anticancer drugs in cell assays. 5FDBI is metabolized through a number of metabolic transformations, including carbonylation and cyclization, yielding different metabolites with different biological activities. These metabolites are not as potent as 5FDBI and have been found to have inhibitory effects on cell proliferation. The antiproliferative activity of 5FDBI is also due to its ability to induce oxidative stress in cells by producing reactive oxygen species (ROS).
Chemical properties
Technical inquiry about: 3D-FF41960 5-Fluoro-1,3-dihydrobenzoimidazol-2-one
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