4-Fluoro-2-(trifluoromethyl)phenylboronic acid

CAS: 182344-16-7

Ref. 3D-FF42787

Product Information

• Name: 4-Fluoro-2-(trifluoromethyl)phenylboronic acid
• Synonyms: (4-Fluoro-2-trifluoromethylphenyl)boronic acid, Akos Brn-1027, B-[4-Fluoro-2-(trifluoromethyl)phenyl]boronic acid, Boronic acid, B-[4-fluoro-2-(trifluoromethyl)phenyl]-, Boronic acid, [4-fluoro-2-(trifluoromethyl)phenyl]-, [4-Fluoro-2-(Trifluoromethyl)Phenyl]Boronic Acid
• CAS: 182344-16-7

Description

The process development of 4-fluoro-2-(trifluoromethyl)phenylboronic acid (4FTFPBA) is a simplified procedure that can be scaled up and used for medicinal chemistry. This compound was synthesized by a boronic acid process using the Suzuki-Miyaura cross coupling reaction. The major factor to consider in this synthesis is the placement of the fluorine atom, which determines the relative reactivity and stability of the compound. In order to mimic these factors, an environment with low water content and a sequence that minimizes exposure to air are required.

• Brand: Biosynth

Chemical properties

• Molecular weight: 207.92 g/mol
• Formula: C₇H₅BF₄O₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C7H5BF4O2/c9-4-1-2-6(8(13)14)5(3-4)7(10,11)12/h1-3,13-14H
• InChI key: InChIKey=SWUPLEAGZOKLNX-UHFFFAOYSA-N
• SMILES: OB(O)c1ccc(F)cc1C(F)(F)F