Fmoc-O-tert-butyl-L-trans-4-hydroxyproline

CAS: 122996-47-8

Ref. 3D-FF47341

Product Information

• Name: Fmoc-O-tert-butyl-L-trans-4-hydroxyproline
• Synonyms: Fmoc-L-Hyp(tBu)-OH, Fmoc-Hyp(tBu)-OH, Fmoc-Hyp(But)-OH, (4R)-4-tert-butoxy-1-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-proline, 4-tert-butoxy-1-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-proline, Fmoc-4-tert-butoxy-L-proline
• CAS: 122996-47-8

Description

Fmoc-O-tert-butyl-L-trans-4-hydroxyproline is a synthetic, cleavable peptide that can be used as a biomaterial. It is synthesized by coupling Fmoc-O-(tert-butoxycarbonyl)-L-trans(4R)-hydroxyproline with the amino acid N,N'-diisopropylcarbodiimide and 4-(dimethylamino)pyridine in a microwave reactor. The peptide has been shown to inhibit the enzyme matrix metalloproteinase 9 (MMP9), which plays an important role in tumor cell invasion and metastasis. This compound also has the ability to form conjugates with other molecules, such as lipopeptides, which may improve its therapeutic potential.

• Brand: Biosynth

Chemical properties

• Molecular weight: 409.47 g/mol
• Formula: C₂₄H₂₇NO₅
• Purity: Min. 98 Area-%
• Color/Form: White Powder