Fmoc-O-benzylphospho-L-serine

CAS: 158171-14-3

Ref. 3D-FF47773

Product Information

• Name: Fmoc-O-benzylphospho-L-serine
• Synonyms: Fmoc-L-Ser(HPO3Bzl)-OH, Fmoc-L-Ser(Po(Obzl)Oh), Fmoc-L-Ser(Po(Obzl)Oh)-Oh, Fmoc-L-Phosphoserine, Fmoc-O-Benzyl-L-Phosphoserine, Fmoc-Ser(Po(Obzl)Oh)-Oh, Fmoc-Ser(HPO3Bzl)-OH, Fmoc-Serine(Po(Obzl)Oh)-Oh, O-[(benzyloxy)(hydroxy)phosphoryl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-serine, Fmoc-Ser(PO(OBzl))-OH

Description

Fmoc-O-benzylphospho-L-serine is a phosphoserine derivative that is used in organic synthesis. It is a metastable compound that has been isolated with a yield of 45%. Fmoc-O-benzylphospho-L-serine can be synthesized on the solid phase by manual means, or it can be synthesized in high yields using the methods of matrix assisted laser desorption/ionization (MALDI) and dipole electrostatic ionization (DESI). The molecular ion peaks at m/z 955.9, and the mass spectrum also contains peaks for dendron ions at m/z 889.5, and matrix ions at m/z 771.5. Fmoc-O-benzylphospho-L-serine is an inhibitor of p53 activity in body fluids such as serum and urine. It also possesses toxic activity against cancer cells,

• Brand: Biosynth

Chemical properties

• Molecular weight: 497.43 g/mol
• Formula: C₂₅H₂₄NO₈P
• Purity: Min. 97 Area-%
• Color/Form: White Off-White Powder
• InChI: InChI=1S/C25H24NO8P/c27-24(28)23(16-34-35(30,31)33-14-17-8-2-1-3-9-17)26-25(29)32-15-22-20-12-6-4-10-18(20)19-11-5-7-13-21(19)22/h1-13,22-23H,14-16H2,(H,26,29)(H,27,28)(H,30,31)/t23-/m0/s1
• InChI key: InChIKey=ZBPUWGDUVAAWJY-QHCPKHFHSA-N
• SMILES: O=C(N[C@@H](COP(=O)(O)OCc1ccccc1)C(=O)O)OCC1c2ccccc2-c2ccccc21