Fmoc-4-amino-1-methylpyrrole-2-carboxylic acid

CAS: 195387-29-2

Ref. 3D-FF56188

Product Information

• Name: Fmoc-4-amino-1-methylpyrrole-2-carboxylic acid
• Synonyms: Fmoc-Py-OH, 4-(9-Fluorenylmethoxycarbonyl)Amino-1-Methylpyrrole-2-Carboxylic Acid, 4-(Fmoc-Amino)-1-Methyl-1H-Pyrrole-2-Carboxlyic Acid, 4-(Fmoc-Amino)-1-Methyl-1H-Pyrrole-2-Carboxylic Acid, 4-(Fmoc-Amino)-1-Methylpyrrol-2-Carboxylic Acid, Fmoc-Py-Oh, Fmoc-Nh(4)-Mepyl-(2)-Oh, Fmoc-4-Amino-1-Methylpyrrole-2-Carboxylic Acid, 4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-1-methyl-1H-pyrrole-2-carboxylic acid

Description

Fmoc-4-amino-1-methylpyrrole-2-carboxylic acid is a bimodal tyrosine phosphatase inhibitor. It has been shown to have a broad range of specificities for the various phosphatases, and is active against many different tyrosine phosphatases. Fmoc-4-amino-1-methylpyrrole-2-carboxylic acid has also been found to be more hydrophobic than other inhibitors, making it more difficult for enzymes to bind. Molecular modeling has shown that this compound binds in a sequence specific manner, which may be an important factor in its effectiveness. In addition, Fmoc-4-amino-1-methylpyrrole-2 carboxylic acid can be synthesized on a solid phase using the technique of solid phase synthesis (SPPS). The compound is synthesized by reacting 4-(dimethylamino)pyrrole

• Brand: Biosynth

Chemical properties

• Molecular weight: 362.38 g/mol
• Formula: C₂₁H₁₈N₂O₄
• Purity: Min. 95%
• InChI: InChI=1S/C21H18N2O4/c1-23-11-13(10-19(23)20(24)25)22-21(26)27-12-18-16-8-4-2-6-14(16)15-7-3-5-9-17(15)18/h2-11,18H,12H2,1H3,(H,22,26)(H,24,25)
• InChI key: InChIKey=GHRPKWXGCOWBLD-UHFFFAOYSA-N
• SMILES: Cn1cc(NC(=O)OCC2c3ccccc3-c3ccccc32)cc1C(=O)O