Fmoc-Glu(Odmab)-OH

CAS: 268730-86-5

Ref. 3D-FF72184

Product Information

• Name: Fmoc-Glu(Odmab)-OH
• Synonyms: N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamic acid 5-[[4-[[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]phenyl]methyl] ester

Description

Fmoc-Glu(Odmab)-OH is a neurotrophic peptide that is derived from glutamate and has been shown to be neuroprotective in cell culture. The peptide has been shown to have antioxidative activity, which may be due to its ability to scavenge reactive oxygen species (ROS) and reactive nitrogen species (RNS). Fmoc-Glu(Odmab)-OH has also been shown to reduce oxidative stress in brain homogenates by preventing lipid peroxidation. In addition, Fmoc-Glu(Odmab)-OH can chelate iron and inhibit the formation of the hydroxyl radical. Fmoc-Glu(Odmab)-OH may have potential as a drug for neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 680.79 g/mol
• Formula: C₄₀H₄₄N₂O₈
• Purity: Min. 95%
• InChI: InChI=1S/C40H44N2O8/c1-24(2)19-33(37-34(43)20-40(3,4)21-35(37)44)41-26-15-13-25(14-16-26)22-49-38(47)32(17-18-36(45)46)42-39(48)50-23-31-29-11-7-5-9-27(29)28-10-6-8-12-30(28)31/h5-16,24,31-32,43H,17-23H2,1-4H3,(H,42,48)(H,45,46)/b41-33+/t32-/m0/s1
• InChI key: InChIKey=NPQLJRFJRUQEMA-GQVZARDDSA-N
• SMILES: CC(C)C/C(=N\c1ccc(COC(=O)[C@H](CCC(=O)O)NC(=O)OCC2c3ccccc3-c3ccccc32)cc1)C1=C(O)CC(C)(C)CC1=O