Fmoc-D-b-Phe(2-Cl)-OH

CAS: 511272-52-9

Ref. 3D-FF72564

Product Information

• Name: Fmoc-D-b-Phe(2-Cl)-OH
• Synonyms: benzenepropanoic acid, 2-chloro-beta-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (betaR)-, Fmoc-(R)-3-Amino-3-(2-chlorophenyl)-propionic acid, Fmoc-(R)-3-Amino-3-(2-Chloro-Phenyl)-Propionic Acid, (3R)-3-(2-Chlorophenyl)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid

Description

Fmoc-D-b-Phe(2-Cl)-OH is a hydrophobic, non-selective, acetylcholine receptor antagonist that is used to block the transmission of nerve impulses. It has been shown to be neuroprotective in animal models of neurodegenerative disease and to reduce symptoms associated with these diseases. Fmoc-D-b-Phe(2-Cl)-OH prevents the degradation of acetylcholine by acting as an inhibitor of choline esterase, which breaks down acetylcholine. This drug also inhibits the binding of other neurotransmitters, such as dopamine and serotonin, with their receptors.

• Brand: Biosynth

Chemical properties

• Molecular weight: 421.87 g/mol
• Formula: C₂₄H₂₀ClNO₄
• Purity: Min. 95%
• InChI: InChI=1S/C24H20ClNO4/c25-21-12-6-5-11-19(21)22(13-23(27)28)26-24(29)30-14-20-17-9-3-1-7-15(17)16-8-2-4-10-18(16)20/h1-12,20,22H,13-14H2,(H,26,29)(H,27,28)/t22-/m1/s1
• InChI key: InChIKey=MHQMTMDZWLOODM-JOCHJYFZSA-N
• SMILES: O=C(O)C[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)c1ccccc1Cl