5-Fluoro-2,3-dihydro-1H-isoindole

CAS: 57584-71-1

Ref. 3D-FF81013

Product Information

• Name: 5-Fluoro-2,3-dihydro-1H-isoindole
• Synonyms: 1H-isoindole, 5-fluoro-2,3-dihydro-, 5-Fluoroisoindoline

Description

5-Fluoro-2,3-dihydro-1H-isoindole is a potent inhibitor of peptidases. It is structurally related to the isoindolines and has been reported to be an inhibitor of dipeptidyl peptidase IV (DPPIV) from human blood cells and of aminopeptidases from rat brain. 5-Fluoro-2,3-dihydro-1H-isoindole binds to the active site of DPPIV, blocking access for peptide substrates. The inhibition of this enzyme by 5-fluoro-2,3-dihydro-1H-isoindole leads to decreased levels of proinsulin in the blood stream. This compound also has affinity for other enzymes such as pepsin and trypsin.

• Brand: Biosynth

Chemical properties

• Molecular weight: 137.15 g/mol
• Formula: C₈H₈FN
• Purity: Min. 95%
• InChI: InChI=1S/C8H8FN/c9-8-2-1-6-4-10-5-7(6)3-8/h1-3,10H,4-5H2
• InChI key: InChIKey=UYIALDLZAMTNLK-UHFFFAOYSA-N
• SMILES: Fc1ccc2c(c1)CNC2