4-Fluoro-2-Methyl-Benzenesulfonamide
CAS: 489-17-8
Ref. 3D-FF82733
| 1g | To inquire | ||
| 2g | To inquire | ||
| 5g | To inquire | ||
| 10g | To inquire | ||
| 500mg | To inquire |
Product Information
- 4-Fluor-2-methylbenzolsulfonamid
- Benzenesulfonamide, 4-fluoro-2-methyl-
The 4-Fluoro-2-Methyl-Benzenesulfonamide is a potent inhibitor of the cyclooxygenase enzyme COX-2. This inhibition leads to decreased production of prostaglandin, which is a mediator of pain and inflammation. The structure activity relationship study showed that these compounds have inhibitory activity on COX-2 with an IC50 value of 0.0027 μM. The sulfonamides are structurally related to aspirin, but they lack the acetyl group at position 3 and contain a sulfonyl group instead. They are used as antiinflammatory agents for the treatment of rheumatoid arthritis and other inflammatory disorders.END>
Chemical properties
Technical inquiry about: 3D-FF82733 4-Fluoro-2-Methyl-Benzenesulfonamide
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