N-[4-(4-Fluorophenyl)Phenyl]-N-Hydroxyacetamide

CAS: 76299-95-1

Ref. 3D-FF90389

Product Information

• Name: N-[4-(4-Fluorophenyl)Phenyl]-N-Hydroxyacetamide

Description

N-[4-(4-Fluorophenyl)Phenyl]-N-Hydroxyacetamide is a reactive compound that terminates DNA replication in the presence of single-stranded DNA. It reacts with the 3' hydroxyl group of a nucleotide to form a stable, covalent bond. The reaction products are detected by high performance liquid chromatography (HPLC). This termination reaction has been shown to produce clastogenic effects in animals. N-[4-(4-Fluorophenyl)Phenyl]-N-Hydroxyacetamide has also been shown to be toxic and carcinogenic in Sprague-Dawley rats as well as other animal models.

• Brand: Biosynth

Chemical properties

• Molecular weight: 245.25 g/mol
• Formula: C₁₄H₁₂FNO₂
• Purity: Min. 95%
• InChI: InChI=1S/C14H12FNO2/c1-10(17)16(18)14-8-4-12(5-9-14)11-2-6-13(15)7-3-11/h2-9,18H,1H3
• InChI key: InChIKey=HGGMLBWJBWVFRN-UHFFFAOYSA-N
• SMILES: CC(=O)N(O)c1ccc(-c2ccc(F)cc2)cc1