4-Fluoropyridine-2-carboxylic acid

CAS: 886371-78-4

Ref. 3D-FF95352

Product Information

• Name: 4-Fluoropyridine-2-carboxylic acid
• Synonyms: 2-Pyridinecarboxylic acid, 4-fluoro-, 4-Fluoro-2-pyridinecarboxylic acid, 4-Fluoro-Pyridine-2-Carboxylic Acid

Description

4-Fluoropyridine-2-carboxylic acid (4-FP) is a monoaminergic agent that binds to the metabotropic glutamate receptor type 2 (mGluR2). It has been shown to be effective in treating depression and anxiety. 4-FP is a modulator of the mGluR2 receptor, which is an allosteric site on the receptor. The binding site for 4-FP is on the extracellular side of the mGluR2 receptor, where it acts as a competitive antagonist by blocking glutamate from binding. This may be due to its ability to increase serotonin levels in the brain by inhibiting serotonin reuptake.

• Brand: Biosynth

Chemical properties

• Molecular weight: 141.1 g/mol
• Formula: C₆H₄FNO₂
• Purity: Min. 95%
• InChI: InChI=1S/C6H4FNO2/c7-4-1-2-8-5(3-4)6(9)10/h1-3H,(H,9,10)
• InChI key: InChIKey=DOJINJNLDNIFBN-UHFFFAOYSA-N
• SMILES: O=C(O)c1cc(F)ccn1